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|
Variable
|
HFpEF (n = 37)
|
non-HF (n = 302)
|
P
|
|---|
|
Female (n (%))
|
25(68%)
|
147(49%)
|
0.036
|
|
Age (year)
|
68 ± 2
|
62 ± 1
|
0.013
|
|
HR (beats/min)
|
75 ± 2
|
70 ± 1
|
0.150
|
|
BMI (kg/m2)
|
24.4 ± 0.7
|
24.1 ± 0.2
|
0.828
|
|
Hypertension
|
29(78%)
|
169(56%)
|
0.012
|
|
CAD
|
9(24%)
|
68(22%)
|
0.836
|
|
CKD(stage ≥ 3)or ESRD
|
8(22%)
|
16(5%)
|
0.002
|
|
COPD
|
1(3%)
|
7(2%)
|
1.000
|
|
Diabetes
|
10(27%)
|
60(20%)
|
0.291
|
|
Mitral E (cm/s)
|
96 ± 4
|
77 ± 1
|
< 0.001
|
|
Mitral A (cm/s)
|
82 ± 6
|
87 ± 1
|
0.249
|
|
E/A ratio
|
0.9(0.8—2.0)
|
0.9(0.7—1.1)
|
0.014
|
|
Septal e′ velocity (cm/s)
|
5.0 ± 0.2
|
6.6 ± 0.1
|
< 0.001
|
|
Lateral e′ velocity (cm/s)
|
6.0(5.0—8)
|
9.0(7.0—11.0)
|
< 0.001
|
|
E/e’ ratio
|
16.2(14.1—16.2)
|
9.9(7.4—14.6)
|
< 0.001
|
|
TR peak velocity (m/s)
|
2.8(2.7—3.0)
|
2.5(2.3—2.7)
|
< 0.001
|
|
LVEF (%)
|
60 ± 1
|
65 ± 1
|
0.001
|
|
LAVimax (ml/m2)
|
42.8 ± 2.0
|
31.2 ± 0.7
|
< 0.001
|
|
LAEF (%)
|
45 ± 3
|
55 ± 1
|
< 0.001
|
|
LASr(%)
|
18.0 ± 1.5
|
28 ± 1
|
< 0.001
|
|
E/LASr ratio
|
4.8(3.2—9.1)
|
2.6(2.0—3.6)
|
< 0.001
|
