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Variable
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LVEDP ≤ 16 mmHg (n = 18)
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LVEDP > 16 mmHg (n = 31)
|
P
|
validation group (n = 339)
|
|---|
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Baseline Characteristics
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Female (n (%))
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4 (22%)
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11 (30.6%)
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0.332
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172 (50.7%)
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Age(year)
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64 ± 2
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63 ± 2
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0.563
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63 ± 1
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HR (beats/min)
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63 ± 2
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68 ± 2
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0.144
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72 ± 1
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BMI(kg/m2)
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24.1 ± 0.7
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24.6 ± 0.5
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0.641
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24.1 ± 0.2
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Medical history, n (%)
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Hypertension
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11 (61%)
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26 (83%)
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0.149
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198 (58.4%)
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CAD
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9 (45%)
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11 (31%)
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0.314
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77 (22.7%)
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CKD(stage ≥ 3)or ESRD
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1 (6%)
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1 (3%)
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1.000
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24 (7.1%)
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COPD
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1 (6%)
|
1 (3%)
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1.000
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8 (2.4%)
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Diabetes
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3 (17%)
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8 (25.8%)
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0.701
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70 (20.6%)
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Medication, n (%)
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β-Blockers
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5 (28%)
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17 (55%)
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0.066
|
——
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ACEI
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5 (28%)
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8 (26%)
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0.880
|
——
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ARBs
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3(17%)
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11 (35.5%)
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0.160
|
——
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Calcium blocker
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5 (28%)
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14 (45%)
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0.368
|
——
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Diuretics
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2 (11%)
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3 (10%)
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0.873
|
——
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Statins
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18 (100%)
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30 (97%)
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1.000
|
——
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Nitrates
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5 (28%)
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8 (26%)
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1.000
|
——
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Antiplatelet drugs
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20 (100%)
|
35 (100%)
|
1.000
|
——
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Angiographic findings
| | | |
——
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Numbers of vessels with significant stenosis > 50%
|
——
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|
1
|
3
|
6
|
1.000
|
——
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|
2
|
2
|
2
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0.974
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——
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3
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2
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2
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0.623
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——
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Vessels with stenosis > 50%
|
——
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|
LM
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1
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2
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1.000
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——
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LAD
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5
|
6
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0.744
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——
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LCX
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5
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2
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1.000
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——
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RCA
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1
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3
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1.000
|
——
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Echocardiographic Variables
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|
Mitral E (cm/s)
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66 ± 2
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71 ± 2
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0.143
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79 ± 1
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Mitral A (cm/s)
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75 ± 4
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88 ± 4
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0.045
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86 ± 1
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E/A ratio
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0.8 (0.7—1.0)
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0.8 (0.7—0.9)
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0.383
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0.9 (0.8—1.1)
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Septal e′ velocity (cm/s)
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6.8 ± 0.5
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6.3 ± 0.3
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0.363
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6.4 ± 0.1
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Lateral e′ velocity (cm/s)
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10 (7.8—12.0)
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8.0 (6.0—10.4)
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0.144
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9(6—11)
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E/e’mean ratio
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8.0 (6.8—10.6)
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10 (8.2—11.2)
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0.078
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10 (8—15)
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TR peak velocity (m/s)
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2.3 (2.1—2.5)
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2.2 (2.1—2.6)
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0.949
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2.5 (2.3—2.8)
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LVEF (%)
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66 ± 2
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64 ± 1
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0.733
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64 ± 1
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LAVimax (ml/m2)
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14.6 ± 1.7
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16.5 ± 1.2
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0.388
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32.5 ± 0.7
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LAEF (%)
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55 ± 2
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55 ± 2
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0.851
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54 ± 1
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LASr(%)
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32.9 ± 1.5
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23.2 ± 1.2
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< 0.001
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27.2 ± 0.5
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E/LASr ratio
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2.0 (1.8—2.2)
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3.0 (2.6—4.0)
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< 0.001
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2.7 (2.1—3.8)
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