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| | Controls (n = 45) | CSFP (n = 60) | P-value |
|---|
| Clinical characteristics |
| Age (yrs) | 55.53 ± 8.44 | 56.52 ± 8.82 | 0.57 |
| Male sex [n(%)] | 21 (47%) | 36 (60%) | 0.18 |
| Systolic blood pressure (mm Hg) | 128.12 ± 14.44 | 125.94 ± 11.42 | 0.41 |
| Diastolic blood pressure (mm Hg) | 76.71 ± 9.93 | 75.78 ± 9.91 | 0.63 |
| Hypertension [n(%)] | 20 (44%) | 26 (43%) | 0.91 |
| Diabetes mellitus [n(%)] | 2 (4%) | 5 (8%) | 0.70 |
| Fasting blood glucose (mmol/L) | 5.41 ± 0.87 | 5.60 ± 0.97 | 0.29 |
| Triglycerides (mmol/L) | 1.41 ± 0.83 | 1.43 ± 0.70 | 0.86 |
| Total cholesterol (mmol/L) | 4.43 ± 0.80 | 4.35 ± 0.85 | 0.90 |
| LDL cholesterol (mmol/L) | 2.67 ± 0.82 | 2.79 ± 0.75 | 0.45 |
| HDL cholesterol (mmol/L) | 1.16 ± 0.30 | 1.07 ± 0.22 | 0.10 |
| TFC |
| cLAD | 21.77 ± 3.23 | 42.16 ± 16.11 | < 0.001 |
| LCX | 21.47 ± 3.85 | 35.77 ± 16.53 | < 0.001 |
| RCA | 21.20 ± 4.11 | 36.82 ± 18.76 | < 0.001 |
| Mean | 21.48 ± 2.27 | 38.25 ± 13.57 | < 0.001 |
| LV systolic function measurements |
| LV end-diastolic volume (ml) | 82.27 ± 15.08 | 85.05 ± 16.92 | 0.38 |
| LV ejection fraction (%) | 64.27 ± 4.44 | 63.03 ± 3.96 | 0.14 |
| LV GLS (%) | −20.58 ± 2.36 | −19.24 ± 2.27 | 0.004 |
| LV diastolic function measurements |
| LA Volmax index | 27.76 ± 7.51 | 31.83 ± 8.47 | 0.03 |
| Mitral E (m/s) | 74.89 ± 15.47 | 66.67 ± 17.24 | 0.01 |
| Mitral E/A | 1.16 ± 0.37 | 0.96 ± 0.29 | 0.003 |
| Mitral e’ (cm/s) | 8.67 ± 2.19 | 7.72 ± 1.69 | 0.01 |
| Mitral E/e’ | 8.99 ± 2.26 | 8.86 ± 2.45 | 0.78 |
| Tricuspid regurgitation velocity (m/s) | 2.01 ± 0.78 | 2.23 ± 0.89 | 0.56 |
- Values shown are means±SD or percentages
- Abbreviation: LDL low-density lipoprotein, HDL high-density lipoprotein, TFC thrombolysis in myocardial infarction frame count, cLAD corrected left anterior descending coronary artery, LCX left circumflex coronary artery, RCA right coronary artery, LV left ventricle, GLS global longitudinal strain, LA Volmax maximal LA volume, E early diastolic flow velocity, A late diastolic flow velocity, e’ early diastolic annular velocity