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Ejection work density (Pa)
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|---|
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All (n = 356)
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Men (n = 197)
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Women (n = 159)
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|---|
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LV diastolic function index
|
Parameter estimate (95% CI)
|
P value
|
Parameter estimate (95% CI)
|
P value
|
Parameter estimate (95% CI)
|
P value
|
P
int
|
|---|
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E peak, + 15 cm/s
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55.3 (33.0 to 77.5)
|
< 0.0001
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38.8 (11.3 to 66.3)
|
0.0059
|
86.7 (51.2 to 122.3)
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< 0.0001
|
0.39
|
|
A peak, + 15 cm/s
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47.2 (20.6 to 73.8)
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0.0005
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43.9 (9.50 to 78.2)
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0.013
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45.5 (39.0 to 87.2)
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0.032
|
0.16
|
|
E/A ratio, + 0.45
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29.1 (−2.30 to 60.4)
|
0.069
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17.0 (−20.9 to 54.9)
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0.38
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58.3 (5.50 to 111.1)
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0.031
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0.39
|
|
e’ peak, + 3.2 cm/s
|
32.2 (−0.031 to 64.3)
|
0.050
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48.6 (10.3 to 87.0)
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0.013
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16.5 (−36.7 to 72.7)
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0.56
|
0.014
|
|
a’ peak, + 2.0 cm/s
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19.7 (−4.97 to 44.4)
|
0.12
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33.9 (5.42 to 52.3)
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0.020
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−8.96 (−51.9 to 34.0)
|
0.68
|
0.75
|
|
E/e’ ratio, + 2.1
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32.1 (9.20 to 55.1)
|
0.0062
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2.45 (−31.1 to 36.1)
|
0.89
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51.1 (19.6 to 82.6)
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0.0017
|
0.0016
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- The parameter estimates (95% confidence interval) indicate the change in EWD per 1 standard deviation increase in the LV diastolic function index. All parameter estimates accounted for the variance explained by age, sex, heart rate and body height and weight. Pint represents the P value for an interaction between each LV diastolic function index and sex in predicting EWD