Fig. 2

The Ejection Work Density (EWD) in Relation to Age (Panels a and b) and Sex (Panel c). Full and dotted lines in Panel a represent the linear regression line and 95% confidence band, respectively. Boxplots present the adjusted mean EWD and 5–95% and 25–75% confidence limits by age tertiles (Panel b) and sex (Panel c). Adjustments in EWD accounted for the variance explained by age (except in a-b), sex (except in c), hypertension, heart rate and body height and weight