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Variable
|
Univariate analysis OR [95% CI]
|
p-value
|
Multivariate analysis OR [95% CI]
|
p-value
|
|---|
|
Age (yrs)
|
0.9 [0.9–1]
|
0.2
| | |
|
Gender Male (%)
|
1.5 [1.3–31]
|
0.06
| | |
|
Diabetes Mellitus (%)
|
0.8 [0.9–1.2]
|
0.2
| | |
|
Hypertension (%)
|
0.9 [0.8–1.1]
|
0.3
| | |
|
Coronary artery disease (%)
|
2.2 [1.01–4.8]
|
0.001
|
2.64 [1.04–6.7]
|
0.04
|
|
CKDa
|
1.7 [1.4–4.3]
|
0.03
| | |
|
NYHA class (%)
|
2 [1.2–3.5]
|
0.05
| | |
|
BNP (pg/ml)
|
1.0 [1–1.01]
|
0.04
| | |
|
Mitral regurgiation (%)
|
3 [1.3–6.5]
|
0.05
| | |
|
Rest E/e’
|
1.05 [0.9–1.2]
|
0.06
| | |
|
Rest ejection fraction (%)
|
1.13 [0.7–1.8]
|
0.59
| | |
|
Peak ejection fraction (%)
|
0.50 [0.3–0.8]
|
0.0059
| | |
|
Rest end-diastolic volume index (ml/m2)
|
1.0 [0.9–1.2]
|
0.97
| | |
|
Peak end-diastolic volume index (ml/m2)
|
1.17 [1.04–1.3]
|
0.07
| | |
|
Rest end-systolic volume index (ml/m2)
|
0.98 [0.8–1.2]
|
0.91
| | |
|
Peak end-systolic volume index (ml/m2)
|
1.81 [1.2–3.1]
|
0.05
| | |
|
Baseline LVMi (g/m2)
|
0.99 [0.97–1.01]
|
0.81
| | |
|
Baseline patterns of LV geometry
|
1.73 [1.3–2.9]
|
0.04
| | |
|
Peak cardiac power output-to-mass (Watt/100 g)
|
0.04 [0.02–0.19]
|
0.01
| | |
|
Peak LV elastance (mmHg/ml/m2)
|
8.3 [3.4–25]
|
< 0.0001
|
12.5 [4.5–33]
|
< 0.0001
|
- Legend: BNP, B-type natriuretic peptide; CKD, chronic kidney disease; E/e’, ratio of mitral E peak velocity and averaged e’ velocity; LV, left ventricular; LVMi, left ventricular mass indexed; NYHA, New York Heart Association
- aChronic kidney disease was defined as eGFR< 60 mL/min/1.73m2
